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Peduncle of midbrain: anatomy, location and function

The cerebral peduncles are paired columns on the ventral midbrain carrying descending fibres from the cerebral cortex. They carry corticospinal, corticobulbar and corticopontine fibres in the crus cerebri to the brainstem and spinal cord.

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Highlighted in the model: Peduncle of midbrain. Click any part to read about it, or switch off “Highlight topic” to see the whole body. 3D data: BodyParts3D, © The Database Center for Life Science, CC BY 4.0; meshes simplified and recoloured. The model is an adult male.

Peduncle of midbrain at a glance

Also called
Cerebral peduncle
What it is
The cerebral peduncles are paired columns on the ventral midbrain carrying descending fibres from the cerebral cortex.
Location
They emerge from the base of the brain on either side of the interpeduncular fossa and run toward the cerebral hemispheres.
Function
They carry corticospinal, corticobulbar and corticopontine fibres in the crus cerebri to the brainstem and spinal cord.
Body system
Nervous · single, midline structure
FMA ID
FMA62394 (Foundational Model of Anatomy)

Key facts

  • Crus cerebri is the anterior part; the tegmentum and substantia nigra lie behind it.
  • The oculomotor nerve emerges medially.

Structures next to the peduncle of midbrain

The nearest named structures in the 3D model, measured from the centre of each part:

References

  1. Foundational Model of Anatomy: Peduncle of midbrain (FMA62394). EMBL-EBI Ontology Lookup Service.
  2. OpenStax. Anatomy and Physiology 2e, §12.1 Basic Structure and Function of the Nervous System. Rice University, 2022.
  3. Mitsuhashi N. et al. (2009). BodyParts3D: 3D structure database for anatomical concepts. Nucleic Acids Research 37, D782–D785. Data © The Database Center for Life Science, CC BY 4.0.

Explore the whole body in the interactive 3D human anatomy model, or browse the A–Z list of human structures.