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Skin: anatomy, location and function

The skin is the body's largest organ, forming a protective covering. It protects against injury, microbes and water loss, regulates temperature, produces vitamin D and senses touch, pain and temperature.

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Skin0%
Muscles100%

Structures

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Highlighted in the model: Skin. Click any part to read about it, or switch off “Highlight topic” to see the whole body. 3D data: BodyParts3D, © The Database Center for Life Science, CC BY 4.0; meshes simplified and recoloured. The model is an adult male.

Skin at a glance

What it is
The skin is the body's largest organ, forming a protective covering.
Location
It covers the entire external body surface, continuous with mucous membranes at the orifices.
Function
It protects against injury, microbes and water loss, regulates temperature, produces vitamin D and senses touch, pain and temperature.
Body system
Skin · single, midline structure
FMA ID
FMA7163 (Foundational Model of Anatomy)

Key facts

  • It has two layers, the epidermis and the dermis; the hypodermis (subcutaneous tissue) beneath anchors it but is not strictly part of the skin.
  • The epidermis is keratinised stratified squamous epithelium with no blood vessels of its own.
  • It makes up about 15 percent of body weight and has a surface area of roughly 1.5–2 square metres in adults.

Clinical relevance

Sun exposure increases the risk of melanoma and other skin cancers.

Structures next to the skin

The nearest named structures in the 3D model, measured from the centre of each part:

References

  1. Foundational Model of Anatomy: Skin (FMA7163). EMBL-EBI Ontology Lookup Service.
  2. OpenStax. Anatomy and Physiology 2e, §5.1 Layers of the Skin. Rice University, 2022.
  3. Mitsuhashi N. et al. (2009). BodyParts3D: 3D structure database for anatomical concepts. Nucleic Acids Research 37, D782–D785. Data © The Database Center for Life Science, CC BY 4.0.

Explore the whole body in the interactive 3D human anatomy model, or browse the A–Z list of human structures.