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Anterior commissure: anatomy, location and function

The anterior commissure is a small bundle of white matter fibres that links the two cerebral hemispheres in front of the fornix columns. Its anterior part connects the olfactory structures and its posterior part mainly connects the temporal lobes, including the amygdalae and temporal cortex of both sides.

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Highlighted in the model: Anterior commissure. Click any part to read about it, or switch off “Highlight topic” to see the whole body. 3D data: BodyParts3D, © The Database Center for Life Science, CC BY 4.0; meshes simplified and recoloured. The model is an adult male.

Anterior commissure at a glance

What it is
The anterior commissure is a small bundle of white matter fibres that links the two cerebral hemispheres in front of the fornix columns.
Location
It crosses the midline in the lamina terminalis, just anterior to the columns of the fornix and below the rostrum of the corpus callosum.
Function
Its anterior part connects the olfactory structures and its posterior part mainly connects the temporal lobes, including the amygdalae and temporal cortex of both sides.
Body system
Nervous · single, midline structure
FMA ID
FMA61961 (Foundational Model of Anatomy)

Key facts

  • Phylogenetically older than the corpus callosum.
  • Forms part of the anterior wall of the third ventricle.

Structures next to the anterior commissure

The nearest named structures in the 3D model, measured from the centre of each part:

References

  1. Foundational Model of Anatomy: Anterior commissure (FMA61961). EMBL-EBI Ontology Lookup Service.
  2. OpenStax. Anatomy and Physiology 2e, §12.1 Basic Structure and Function of the Nervous System. Rice University, 2022.
  3. Mitsuhashi N. et al. (2009). BodyParts3D: 3D structure database for anatomical concepts. Nucleic Acids Research 37, D782–D785. Data © The Database Center for Life Science, CC BY 4.0.

Explore the whole body in the interactive 3D human anatomy model, or browse the A–Z list of human structures.