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Lamina terminalis: anatomy, location and function

The lamina terminalis is a thin sheet of tissue that forms the anterior wall of the third ventricle. It marks the closed anterior end of the embryonic neural tube and forms the front boundary of the third ventricle.

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Highlighted in the model: Lamina terminalis. Click any part to read about it, or switch off “Highlight topic” to see the whole body. 3D data: BodyParts3D, © The Database Center for Life Science, CC BY 4.0; meshes simplified and recoloured. The model is an adult male.

Lamina terminalis at a glance

What it is
The lamina terminalis is a thin sheet of tissue that forms the anterior wall of the third ventricle.
Location
It stretches from the optic chiasm to the anterior commissure and rostrum of the corpus callosum.
Function
It marks the closed anterior end of the embryonic neural tube and forms the front boundary of the third ventricle.
Body system
Nervous · single, midline structure
FMA ID
FMA61975 (Foundational Model of Anatomy)

Key facts

  • Contains the organum vasculosum of the lamina terminalis, a circumventricular organ.
  • It is a common neurosurgical route into the third ventricle (lamina terminalis fenestration).
  • The OVLT within it senses blood osmolality and helps trigger thirst and ADH release.

Structures next to the lamina terminalis

The nearest named structures in the 3D model, measured from the centre of each part:

References

  1. Foundational Model of Anatomy: Lamina terminalis (FMA61975). EMBL-EBI Ontology Lookup Service.
  2. OpenStax. Anatomy and Physiology 2e, §12.1 Basic Structure and Function of the Nervous System. Rice University, 2022.
  3. Mitsuhashi N. et al. (2009). BodyParts3D: 3D structure database for anatomical concepts. Nucleic Acids Research 37, D782–D785. Data © The Database Center for Life Science, CC BY 4.0.

Explore the whole body in the interactive 3D human anatomy model, or browse the A–Z list of human structures.