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Hepatic portal vein: anatomy, location and function

The hepatic portal vein carries nutrient-rich blood from the gut and spleen to the liver. It delivers venous blood from the digestive tract, pancreas, gallbladder and spleen to the liver sinusoids.

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Highlighted in the model: Hepatic portal vein. Click any part to read about it, or switch off “Highlight topic” to see the whole body. 3D data: BodyParts3D, © The Database Center for Life Science, CC BY 4.0; meshes simplified and recoloured. The model is an adult male.

Hepatic portal vein at a glance

What it is
The hepatic portal vein carries nutrient-rich blood from the gut and spleen to the liver.
Location
It forms behind the neck of the pancreas, at about L1-L2, from the superior mesenteric vein and the splenic vein, ascends in the hepatoduodenal ligament and divides into right and left branches at the porta hepatis.
Function
It delivers venous blood from the digestive tract, pancreas, gallbladder and spleen to the liver sinusoids.
Body system
Cardiovascular · single, midline structure
FMA ID
FMA50735 (Foundational Model of Anatomy)

Key facts

  • It provides about three-quarters of liver blood flow.
  • The inferior mesenteric vein most often drains into the splenic vein, but may join the superior mesenteric vein or their junction.
  • It is about 8 cm long.

Clinical relevance

Portal hypertension causes varices at portosystemic anastomoses, ascites and splenomegaly.

Structures next to the hepatic portal vein

The nearest named structures in the 3D model, measured from the centre of each part:

References

  1. Foundational Model of Anatomy: Hepatic portal vein (FMA50735). EMBL-EBI Ontology Lookup Service.
  2. OpenStax. Anatomy and Physiology 2e, §20.1 Structure and Function of Blood Vessels. Rice University, 2022.
  3. Mitsuhashi N. et al. (2009). BodyParts3D: 3D structure database for anatomical concepts. Nucleic Acids Research 37, D782–D785. Data © The Database Center for Life Science, CC BY 4.0.

Explore the whole body in the interactive 3D human anatomy model, or browse the A–Z list of human structures.