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Ileocecal junction: anatomy, location and function

The ileocecal junction is where the terminal ileum opens into the cecum of the large intestine. It regulates passage of material into the large intestine and helps prevent reflux back into the ileum.

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Highlighted in the model: Ileocecal junction. Click any part to read about it, or switch off “Highlight topic” to see the whole body. 3D data: BodyParts3D, © The Database Center for Life Science, CC BY 4.0; meshes simplified and recoloured. The model is an adult male.

Ileocecal junction at a glance

What it is
The ileocecal junction is where the terminal ileum opens into the cecum of the large intestine.
Location
It lies in the right iliac fossa, on the posteromedial wall of the cecum.
Function
It regulates passage of material into the large intestine and helps prevent reflux back into the ileum.
Body system
Digestive · single, midline structure
FMA ID
FMA11338 (Foundational Model of Anatomy)

Key facts

  • The ileocecal valve has two lips with thickened circular muscle. Whether it acts as a true sphincter is debated.
  • After a meal it relaxes as part of the gastroileal reflex.

Clinical relevance

The ileocecal region is a common site of Crohn disease and intestinal tuberculosis, and of ileocolic intussusception in children.

Structures next to the ileocecal junction

The nearest named structures in the 3D model, measured from the centre of each part:

References

  1. Foundational Model of Anatomy: Ileocecal junction (FMA11338). EMBL-EBI Ontology Lookup Service.
  2. OpenStax. Anatomy and Physiology 2e, §23.1 Overview of the Digestive System. Rice University, 2022.
  3. Mitsuhashi N. et al. (2009). BodyParts3D: 3D structure database for anatomical concepts. Nucleic Acids Research 37, D782–D785. Data © The Database Center for Life Science, CC BY 4.0.

Explore the whole body in the interactive 3D human anatomy model, or browse the A–Z list of human structures.