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Ophthalmic nerve: anatomy, location and function

The ophthalmic nerve is the first and smallest division of the trigeminal nerve and is purely sensory. It carries sensation from the eyeball, conjunctiva, lacrimal gland, upper eyelid, forehead, scalp and nose, and part of the nasal cavity and the frontal sinus.

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Highlighted in the model: Ophthalmic nerve. Click any part to read about it, or switch off “Highlight topic” to see the whole body. 3D data: BodyParts3D, © The Database Center for Life Science, CC BY 4.0; meshes simplified and recoloured. The model is an adult male.

Ophthalmic nerve at a glance

What it is
The ophthalmic nerve is the first and smallest division of the trigeminal nerve and is purely sensory.
Location
It runs forward in the lateral wall of the cavernous sinus and divides into the lacrimal, frontal and nasociliary nerves just before the superior orbital fissure.
Function
It carries sensation from the eyeball, conjunctiva, lacrimal gland, upper eyelid, forehead, scalp and nose, and part of the nasal cavity and the frontal sinus.
Body system
Nervous · paired (left and right)
FMA ID
FMA52623 (Foundational Model of Anatomy)

Key facts

  • CN V1.
  • Also supplies meningeal branches to the tentorium cerebelli.

Clinical relevance

Herpes zoster ophthalmicus is a shingles infection of this division.

Structures next to the ophthalmic nerve

The nearest named structures in the 3D model, measured from the centre of each part:

References

  1. Foundational Model of Anatomy: Ophthalmic nerve (FMA52623). EMBL-EBI Ontology Lookup Service.
  2. OpenStax. Anatomy and Physiology 2e, §12.1 Basic Structure and Function of the Nervous System. Rice University, 2022.
  3. Mitsuhashi N. et al. (2009). BodyParts3D: 3D structure database for anatomical concepts. Nucleic Acids Research 37, D782–D785. Data © The Database Center for Life Science, CC BY 4.0.

Explore the whole body in the interactive 3D human anatomy model, or browse the A–Z list of human structures.