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Hippocampus: anatomy, location and function

The hippocampus is a curved cortical structure in the medial temporal lobe that is essential for forming new long-term memories. It is required for consolidating declarative (episodic and semantic) memories and for spatial navigation.

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Highlighted in the model: Hippocampus. Click any part to read about it, or switch off “Highlight topic” to see the whole body. 3D data: BodyParts3D, © The Database Center for Life Science, CC BY 4.0; meshes simplified and recoloured. The model is an adult male.

Hippocampus at a glance

What it is
The hippocampus is a curved cortical structure in the medial temporal lobe that is essential for forming new long-term memories.
Location
It lies in the floor of the temporal horn of the lateral ventricle, within the medial temporal lobe next to the parahippocampal gyrus.
Function
It is required for consolidating declarative (episodic and semantic) memories and for spatial navigation.
Body system
Nervous · paired (left and right)
FMA ID
FMA72714 (Foundational Model of Anatomy)

Key facts

  • Main output is through the fornix.
  • Part of the limbic system and Papez circuit.
  • Subregions include the dentate gyrus and cornu ammonis (CA1 to CA4).
  • Its head bears ridges called the pes hippocampi; the fimbria along its medial edge continues as the crus of the fornix.

Clinical relevance

Hippocampal damage causes anterograde amnesia, and it is among the first regions affected in Alzheimer disease.

Structures next to the hippocampus

The nearest named structures in the 3D model, measured from the centre of each part:

References

  1. Foundational Model of Anatomy: Hippocampus (FMA72714). EMBL-EBI Ontology Lookup Service.
  2. OpenStax. Anatomy and Physiology 2e, §12.1 Basic Structure and Function of the Nervous System. Rice University, 2022.
  3. Mitsuhashi N. et al. (2009). BodyParts3D: 3D structure database for anatomical concepts. Nucleic Acids Research 37, D782–D785. Data © The Database Center for Life Science, CC BY 4.0.

Related anatomy

Explore the whole body in the interactive 3D human anatomy model, or browse the A–Z list of human structures.