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Parahippocampal gyrus: anatomy, location and function

The parahippocampal gyrus is a gyrus on the medial temporal lobe, adjoining the hippocampus. It is involved in memory encoding and retrieval and scene processing, and acts as the main route between the neocortex and hippocampus.

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Highlighted in the model: Parahippocampal gyrus. Click any part to read about it, or switch off “Highlight topic” to see the whole body. 3D data: BodyParts3D, © The Database Center for Life Science, CC BY 4.0; meshes simplified and recoloured. The model is an adult male.

Parahippocampal gyrus at a glance

What it is
The parahippocampal gyrus is a gyrus on the medial temporal lobe, adjoining the hippocampus.
Location
It lies on the medial-inferior surface of the temporal lobe, between the hippocampal sulcus and the collateral sulcus.
Function
It is involved in memory encoding and retrieval and scene processing, and acts as the main route between the neocortex and hippocampus.
Body system
Nervous · paired (left and right)
FMA ID
FMA72706 (Foundational Model of Anatomy)

Key facts

  • Contains the entorhinal cortex at its anterior part.
  • Its anterior end curves into the uncus.

Clinical relevance

Early Alzheimer disease affects the entorhinal cortex.

Structures next to the parahippocampal gyrus

The nearest named structures in the 3D model, measured from the centre of each part:

References

  1. Foundational Model of Anatomy: Parahippocampal gyrus (FMA72706). EMBL-EBI Ontology Lookup Service.
  2. OpenStax. Anatomy and Physiology 2e, §12.1 Basic Structure and Function of the Nervous System. Rice University, 2022.
  3. Mitsuhashi N. et al. (2009). BodyParts3D: 3D structure database for anatomical concepts. Nucleic Acids Research 37, D782–D785. Data © The Database Center for Life Science, CC BY 4.0.

Related anatomy

Explore the whole body in the interactive 3D human anatomy model, or browse the A–Z list of human structures.